Successful Treatment of Amiodarone-induced Thyrotoxicosis Type 1 in Combination with Methimazole and Potassium Iodide in a Patient with Hashimoto's Thyroiditis: A Case Report

Daisuke Katoh; Hiroshi Yoshino; Kayoko Ikehara; Naoki Kumashiro; Hiroshi Uchino; Kumiko Tsuboi; Takahisa Hirose

doi:10.2169/internalmedicine.2179-18

This article has now been updated. Please use the final version.

Successful Treatment of Amiodarone-induced Thyrotoxicosis Type 1 in Combination with Methimazole and Potassium Iodide in a Patient with Hashimoto's Thyroiditis: A Case Report

Daisuke Katoh, Hiroshi Yoshino, Kayoko Ikehara, Naoki Kumashiro, Hiroshi Uchino, Kumiko Tsuboi, Takahisa Hirose

Author information

Daisuke Katoh
Division of Diabetes, Metabolism, and Endocrinology, Department of Medicine, Toho University Graduate School of Medicine, Japan
Hiroshi Yoshino
Division of Diabetes, Metabolism, and Endocrinology, Department of Medicine, Toho University Graduate School of Medicine, Japan
Kayoko Ikehara
Division of Diabetes, Metabolism, and Endocrinology, Department of Medicine, Toho University Graduate School of Medicine, Japan
Naoki Kumashiro
Division of Diabetes, Metabolism, and Endocrinology, Department of Medicine, Toho University Graduate School of Medicine, Japan
Hiroshi Uchino
Division of Diabetes, Metabolism, and Endocrinology, Department of Medicine, Toho University Graduate School of Medicine, Japan
Kumiko Tsuboi
Division of Diabetes, Metabolism, and Endocrinology, Department of Medicine, Toho University Graduate School of Medicine, Japan
Takahisa Hirose
Division of Diabetes, Metabolism, and Endocrinology, Department of Medicine, Toho University Graduate School of Medicine, Japan

Keywords: amiodarone, amiodarone-induced thyrotoxicosis, color flow Doppler sonography, methimazole, potassium iodide

JOURNAL OPEN ACCESS Advance online publication

Article ID: 2179-18

DOI https://doi.org/10.2169/internalmedicine.2179-18

The final version of this article is now available: Vol. 59 (2020), No. 3 pp. 383-388

Details

Abstract

A patient with underlying Hashimoto's thyroiditis developed amiodarone-induced thyrotoxicosis type 1 that was successfully treated using methimazole in combination with potassium iodide. A 35-year-old woman admitted for perinatal care of twin-to-twin transfusion syndrome was given amiodarone for 7 days for paroxysmal ventricular contraction following pulseless ventricular tachycardia 1 day after delivery. She developed thyrotoxicosis one month after the discontinuation of amiodarone therapy and was negative for thyroid-stimulating hormone receptor antibody. An increased peak velocity of the superior thyroid artery suggested amiodarone-induced thyrotoxicosis type 1. Her thyroid function recovered after combination therapy with methimazole and potassium iodide.

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