Hemodialysis-induced Myocardial Stunning with No Obstructive Coronary Artery Disease: Pathophysiological Significance of Coronary Microvascular Dysfunction

Masashi Yokoi; Tsuyoshi Ito; Wataru Suzuki; Junki Yamamoto; Takafumi Nakayama; Taku Ichihashi; Shohei Kikuchi; Shuichi Kitada; Toshihiko Goto; Yoshihiro Seo

doi:10.2169/internalmedicine.2388-23

This article has now been updated. Please use the final version.

Hemodialysis-induced Myocardial Stunning with No Obstructive Coronary Artery Disease: Pathophysiological Significance of Coronary Microvascular Dysfunction

Masashi Yokoi, Tsuyoshi Ito, Wataru Suzuki, Junki Yamamoto, Takafumi Nakayama, Taku Ichihashi, Shohei Kikuchi, Shuichi Kitada, Toshihiko Goto, Yoshihiro Seo

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Keywords: myocardial stunning, myocardial ischemia, coronary microvascular dysfunction, coronary flow reserve, index of microvascular resistance

JOURNAL OPEN ACCESS Advance online publication

Article ID: 2388-23

DOI https://doi.org/10.2169/internalmedicine.2388-23

The final version of this article is now available: Vol. 63 (2024), No. 14 pp. 2023-2026

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Abstract

Hemodialysis (HD)-induced myocardial stunning, characterized by transient left ventricular systolic dysfunction during HD, has been reported to be common and associated with a poor prognosis. However, the pathophysiology is not fully understood. We herein report a case of HD-induced myocardial stunning without obstructive coronary artery disease complicated by coronary microvascular dysfunction (CMD), suggesting that CMD plays a crucial role in the pathophysiology of this disease.

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