Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Simultaneous Occurrence of Sarcoidosis and Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis in a Patient with Lung Cancer
Kazuo TsuchiyaMasato KarayamaTaichi SatoHideki YasuiHironao HozumiYuzo SuzukiKazuki FuruhashiNoriyuki EnomotoTomoyuki FujisawaYutaro NakamuraNaoki InuiHaruhiko SugimuraHideo YasudaTakafumi Suda
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JOURNALS OPEN ACCESS Advance online publication

Article ID: 3004-19

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Abstract

A 71-year-old woman with abnormal pulmonary shadows and multiple enlarged thoracic lymph nodes was diagnosed with stage IIB lung adenocarcinoma, pulmonary sarcoidosis, and sarcoidosis-associated lymphadenopathy after biopsies from multiple organ sites. She also had rapidly progressive renal dysfunction, microhematuria, and high myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) concentrations. A renal biopsy revealed granulomatous tubulointerstitial nephritis and necrotizing glomerulonephritis with crescent formation. She was diagnosed with nephritis caused by both sarcoidosis and ANCA-associated vasculitis. Oral prednisolone was administered to treat her nephritis, resulting in improvement in both her renal dysfunction and her sarcoidosis-associated lymphadenopathy.

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© 2020 by The Japanese Society of Internal Medicine
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