Successful Outcome in an Adult Patient with Influenza-associated Hemorrhagic Shock and Encephalopathy Syndrome

Yasuhiro Komori; Naohiro Uchida; Naoko Soejima; Yasuhiro Fujita; Hiroyuki Matsumoto

doi:10.2169/internalmedicine.4312-19

This article has now been updated. Please use the final version.

Successful Outcome in an Adult Patient with Influenza-associated Hemorrhagic Shock and Encephalopathy Syndrome

Yasuhiro Komori, Naohiro Uchida, Naoko Soejima, Yasuhiro Fujita, Hiroyuki Matsumoto

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Keywords: Hemorrhagic shock and encephalopathy syndrome, Influenza, HSES, Influenza-associated encephalopathy, IAE

JOURNAL OPEN ACCESS Advance online publication

Article ID: 4312-19

DOI https://doi.org/10.2169/internalmedicine.4312-19

The final version of this article is now available: Vol. 59 (2020), No. 18 pp. 2321-2326

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Abstract

A 50-year-old woman presented with coma and hemorrhagic shock. A rapid influenza antigen test revealed influenza A infection; other laboratory examinations ruled out any other suspected infections. She was diagnosed with hemorrhagic shock and encephalopathy syndrome (HSES) induced by influenza A. She was administered methylprednisolone pulse therapy and peramivir. Subsequently, she was discharged without any sequelae. Only a few cases of influenza-induced HSES have been reported, and the clinical outcomes were very poor. We herein report a successfully treated adult case of influenza-induced HSES and review this rare syndrome.

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