Periarterial Fat Stranding as a Diagnostic Marker for Visceral Disseminated Varicella-Zoster Virus Infection

Yoshihide Matsumoto; Kento Ogawa; Hiroaki Hirakawa; Akiko Shimizu; Shigenobu Kuroki; Kozo Ikuta; Eri Senda; Seiji Shio

doi:10.2169/internalmedicine.4478-24

This article has now been updated. Please use the final version.

Periarterial Fat Stranding as a Diagnostic Marker for Visceral Disseminated Varicella-Zoster Virus Infection

Yoshihide Matsumoto, Kento Ogawa, Hiroaki Hirakawa, Akiko Shimizu, Shigenobu Kuroki, Kozo Ikuta, Eri Senda, Seiji Shio

Author information

Keywords: visceral disseminated VZV infection, periarterial fat stranding, VZV-DNA quantification in the stomach, prophylactic valacyclovir

JOURNAL OPEN ACCESS Advance online publication

Article ID: 4478-24

DOI https://doi.org/10.2169/internalmedicine.4478-24

The final version of this article is now available: Vol. 64 (2025), No. 12 pp. 1926-1932

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Abstract

A 61-year-old man who underwent allogeneic bone marrow transplantation presented to our hospital with severe abdominal pain and no significant rash. Computed tomography revealed periarterial fat stranding around the celiac and superior mesenteric arteries. Skin and gastric biopsies revealed varicella-zoster virus (VZV) infection, leading to the diagnosis of VZV infection. Symptoms of VZV infection are severe and potentially fatal, making early intervention important. The characteristic findings of periarterial fat stranding around the celiac and superior mesenteric arteries on CT may play an important role in the early diagnosis of VZV infection.

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