Native Valve Endocarditis due to Staphylococcus warneri Developing in a Patient with Type 1 Diabetes

Junpei Yamamoto; Akira Endo; Hiroto Sugawara; Tomohito Izumi; Kenji Takahashi; Saori Yamamoto; Masatoshi Akiyama; Osamu Adachi; Keizo Kaneko; Shojiro Sawada; Junta Imai; Yoshikatsu Saiki; Hiroaki Shimokawa; Hideki Katagiri

doi:10.2169/internalmedicine.4661-20

This article has now been updated. Please use the final version.

Native Valve Endocarditis due to Staphylococcus warneri Developing in a Patient with Type 1 Diabetes

Junpei Yamamoto, Akira Endo, Hiroto Sugawara, Tomohito Izumi, Kenji Takahashi, Saori Yamamoto, Masatoshi Akiyama, Osamu Adachi, Keizo Kaneko, Shojiro Sawada, Junta Imai, Yoshikatsu Saiki, Hiroaki Shimokawa, Hideki Katagiri

Author information

Junpei Yamamoto
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan
Akira Endo
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan
Hiroto Sugawara
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan
Tomohito Izumi
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan
Kenji Takahashi
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan
Saori Yamamoto
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan
Masatoshi Akiyama
Division of Cardiovascular Surgery, Tohoku University Hospital, Japan
Osamu Adachi
Division of Cardiovascular Surgery, Tohoku University Hospital, Japan
Keizo Kaneko
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan
Shojiro Sawada
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan
Junta Imai
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan
Yoshikatsu Saiki
Division of Cardiovascular Surgery, Tohoku University Hospital, Japan
Hiroaki Shimokawa
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan
Hideki Katagiri
Department of Diabetes and Metabolism, Tohoku University Hospital, Japan

Keywords: Infective endocarditis (IE), Native valve endocarditis (NVE), Coagulase-negative staphylococcus (CoNS), Staphylococcus warneri, Diabetes mellitus, Bicuspid aortic valve

JOURNAL OPEN ACCESS Advance online publication

Article ID: 4661-20

DOI https://doi.org/10.2169/internalmedicine.4661-20

The final version of this article is now available: Vol. 59 (2020), No. 18 pp. 2269-2274

Details

Abstract

A 59-year-old man with type 1 diabetes presented with heart failure. Echocardiography showed large vegetations on the mitral and aortic valves. Blood bacterial culture was positive for Staphylococcus warneri, a coagulase-negative staphylococcus (CoNS) family member. He was diagnosed with native valve endocarditis (NVE) induced by the resident bacteria and ultimately underwent double valve replacement. Retrospectively, slight laboratory data abnormalities and weight loss beginning four months before may have been signs of NVE. He had no history of immunosuppressive therapies or medical device implantation. Thus, CoNS can cause NVE after a long asymptomatic course in patients with poorly controlled diabetes.

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