Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
A case of Sjögren's syndrome with sensory neuronopathy and polyradiculoneuropathy
Takumi FunakoshiMinoru YamadaKazuna IkedaKazuki YokokawaTarou SaitoReiko TsudaNaotoshi IwaharaSyuuichirou SuzukiShin Hisahara
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JOURNAL OPEN ACCESS Advance online publication

Article ID: 5188-24

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Abstract

41-year-old female became difficulty walking due to sensory ataxia in the limbs and trunk. A diagnosis of Sjögren's syndrome was made on the results of positive anti-SS-A antibody and a lip gland biopsy. Nerve conduction studies indicated sensory neuronopathy. The symptoms improved following treatment with plasma exchange, intravenous immunoglobulin, and intravenous methylprednisolone. Nine months later, the patient's sensory ataxia worsened. Nerve conduction studies revealed the coexistence of sensory neuronopathy and polyradiculoneuropathy. The symptoms improved following treatment with intravenous cyclophosphamide and intravenous immunoglobulin. This case represents the first instance of sensory neuronopathy and polyradiculoneuropathy coexisting as Sjögren's syndrome related neuropathy.

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