Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Varicella Zoster Virus Vasculopathy Leading to a Recurrent Cerebral Infarction: Differential Treatment Responses Between Stenosis and Occlusion
Hideyuki ShimizuKenichi SakutaMotohiro OkumuraYasuyuki Iguchi
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JOURNAL OPEN ACCESS Advance online publication

Article ID: 5262-25

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Abstract

Varicella zoster virus (VZV) infection can cause vasculopathy and stroke; however, the response of VZV-induced vasculopathy to treatment is still not well understood. We herein report the case of a 41-year-old man with a recurrent cerebral infarction following herpes zoster infection. The patient presented with a visual field disturbance and a history of myelodysplastic syndrome and chronic kidney disease. Magnetic resonance imaging (MRI) revealed multiple vascular stenoses and occlusions. Despite initial antiviral and steroid therapy, his condition worsened and he required additional treatment. Vessel stenosis responded well to treatment, whereas occlusion did not. An early diagnosis and prompt treatment of VZV-induced vasculopathy are crucial for preventing irreversible vascular damage.

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© 2025 by The Japanese Society of Internal Medicine

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