Management of Advanced Lung Cancer in Pregnancy: Multidisciplinary Treatment and Early Delivery; A Case Report

Hiroaki Nagamine; Hiroyasu Kaneda; Syotaro Yamamoto; Kohei Kitada; Yoko Tani; Takako Oka; Yoshiya Matsumoto; Toshiyuki Nakai; Kazuhiro Yamada; Tetsuya Watanabe; Kazuhisa Asai; Yoshitaka Nakao; Daisuke Tachibana; Tomoya Kawaguchi

doi:10.2169/internalmedicine.5355-25

Hiroaki Nagamine, Hiroyasu Kaneda, Syotaro Yamamoto, Kohei Kitada, Yoko Tani, Takako Oka, Yoshiya Matsumoto, Toshiyuki Nakai, Kazuhiro Yamada, Tetsuya Watanabe, Kazuhisa Asai, Yoshitaka Nakao, Daisuke Tachibana, Tomoya Kawaguchi

Author information

Hiroaki Nagamine
Department of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, Japan
Hiroyasu Kaneda
Department of Clinical Oncology, Graduate School of Medicine, Osaka Metropolitan University, Japan
Syotaro Yamamoto
Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, Japan
Kohei Kitada
Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, Japan
Yoko Tani
Department of Clinical Oncology, Graduate School of Medicine, Osaka Metropolitan University, Japan
Takako Oka
Department of Clinical Oncology, Graduate School of Medicine, Osaka Metropolitan University, Japan
Yoshiya Matsumoto
Department of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, Japan
Toshiyuki Nakai
Department of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, Japan
Kazuhiro Yamada
Department of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, Japan
Tetsuya Watanabe
Department of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, Japan
Kazuhisa Asai
Department of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, Japan
Yoshitaka Nakao
Department of Clinical Oncology, Graduate School of Medicine, Osaka Metropolitan University, Japan
Daisuke Tachibana
Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, Japan
Tomoya Kawaguchi
Department of Respiratory Medicine, Graduate School of Medicine, Osaka Metropolitan University, Japan
Department of Clinical Oncology, Graduate School of Medicine, Osaka Metropolitan University, Japan

Keywords: advanced care planning, case report, multidisciplinary team, lung cancer, palliative care, pregnancy

JOURNAL OPEN ACCESS Advance online publication

Article ID: 5355-25

DOI https://doi.org/10.2169/internalmedicine.5355-25

Details

Abstract

The poor prognosis of lung cancer during pregnancy requires complicated management. A 40-year-old woman at 25 weeks' gestation was admitted with persistent back pain. Imaging findings suggested lung cancer. A multidisciplinary team determined that early intervention was crucial, and Caesarean delivery was performed at 27 weeks' gestation. Thereafter, the patient was diagnosed with lung adenocarcinoma with bone metastasis. The patient underwent rapid opioid titration and radiation therapy for the bone metastases. We then introduced chemotherapy and offered an advanced care plan. A multidisciplinary approach is essential for pregnant women with lung cancer. Early delivery is recommended to expedite the diagnosis and treatment.

Corresponding author

Register with J-STAGE for free!