A Case of Heyde Syndrome Complicated by Alcoholic Liver Cirrhosis in which Aortic Valve Stenosis Was Diagnosed due to Gastrointestinal Bleeding

Abstract

A man in his 60s with alcoholic cirrhosis experienced repeated gastrointestinal bleeding, and endoscopy revealed angiodysplasia hemorrhaging in the stomach and duodenum. A systolic murmur was heard, and cardiology consultation resulted in the diagnosis of severe aortic stenosis and Heyde syndrome. Gastrointestinal bleeding was resolved after surgical aortic valve replacement. Gastrointestinal bleeding often occurs in patients with cirrhosis and a cardiac examination is recommended if angiodysplasia is observed. This case also suggests that the von Willebrand factor, which is involved in Heyde syndrome, is also closely associated with liver disease.