Transient Antiphospholipid Antibody Positivity in a Patient with Cerebral Infarction Due to Vertebral Artery Dissection: A Case Report and Literature Review

Abstract

We herein report a 60-year-old man with transient lupus anticoagulant positivity in the acute phase of cerebral infarction due to left vertebral artery dissection who experienced repeated occlusion of the affected artery despite mechanical thrombectomy and stent placement. The addition of anticoagulants prevented further cerebral infarctions. In this case, it was believed that vascular injury caused by vertebral artery dissection, combined with the presence of antiphospholipid antibodies, accelerated repeated thrombosis. Interestingly, anti-cardiolipin antibodies were detected eight months later, although all antiphospholipid antibodies were negative at the time of the first follow-up.