Ectopic ACTH-, β-LPH- and β-Endorphin-producing Metastatic Carcinoma of the Lung from the Tonsil

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A rare case of metastatic lung cancer from the tonsil associated with ectopic ACTH, β-LPH and β-endorphin production was presented. A year after the tonsillectorny and lymphadenectomy, the patient had metastatic lung cancer. Three years later he died. Brownpigmentation remained evident for a month before his death. Both ACTHand cortisol levels were high in the plasma. ACTH, β-LPH and β-endorphin were found in the tissue extracts (squamouscell carinoma).