1986 年 25 巻 2 号 p. 175-178
A case of an LDH-IgG complex formation which causes low plasma LDH activity and an abnormal LDH isozyme pattern was reported. A patient had pericarditis and myocardial hypertrophy of asymmetrical septal hypertrophy type. The same IgG was recognized in pericardial effusion. From a column chromatographic study, the molecular weight of LDH-IgG complex was estimated as being about 490, 000. This complex was speculated as the IgG1 -LDH2. The mechanism by which LDH-IgG is formed and the relationship between the complex itself and cardiac diseases remain unknown.