A Study of the Clinical Significance of Lipoprotein (a) in Nephrotic Syndrome

Tadayoshi TAKEGOSHI; Chikashi KITOH; Toshihiro HABA; Jun-ichi HIRAI; Takanobu WAKASUGI; Takashi SAGA; Yoshikiyo YAMAZAKI; Hiroshi MABUCHI

doi:10.2169/internalmedicine1962.30.21

Tadayoshi TAKEGOSHI, Chikashi KITOH, Toshihiro HABA, Jun-ichi HIRAI, Takanobu WAKASUGI, Takashi SAGA, Yoshikiyo YAMAZAKI, Hiroshi MABUCHI

著者情報

キーワード: Atherosclerosis, HyperLp(a)aemia

ジャーナルフリー

1991 年 30 巻 1 号 p. 21-25

DOI https://doi.org/10.2169/internalmedicine1962.30.21

詳細

Published: 1991 Received: 1989/12/21 Available on J-STAGE: 2006/03/27 Accepted: 1990/09/18 Advance online publication: - Revised: -
訂正情報
訂正日: 2006/03/27 訂正理由: - 訂正箇所: 論文抄録訂正内容: Wrong : Lipoprotein (Lp)(a) concentrations were measured in eight patients with nephrotic syndrome in the age range of 8 to 69 yrs. Mean (±SE) levels of serum Lp(a) were elevated in the nephrotic patients compared to controls (76.5±19.7 vs 18.6±0.9 mg/dl, p<0.001). After treatment with prednisolone, Lp(a) concentrations were decreased from 85.2±21.6 to 42.2±14.0 mg/dl. During the treatment, serum total cholesterol showed a negative correlation with serum albumin concentration. However, no correlation was noted between Lp(a) and serum albumin concentration. There were no significant correlations between Lp(a) and other lipoprotein lipid and apolipoprotein levels. It was concluded that hyperLp(a) aemia may be an independent risk factor in the development of premature atherosclerosis in patients with nephrotic syndrome.
Right : Lipoprotein (Lp)(a) concentrations were measured in eight patients with nephrotic syndrome in the age range of 8 to 69 yrs. Mean (±SE) levels of serum Lp(a) were elevated in the nephrotic patients compared to controls (76.5±19.7 vs 18.6±0.9 mg/dl, p<0.001). After treatment with prednisolone, Lp(a) concentrations were decreased from 85.2±21.6 to 42.2±14.0 mg/dl. During the treatment, serum total cholesterol showed a negative correlation with serum albumin concentration. However, no correlation was noted between Lp(a) and serum albumin concentration. There were no significant correlations between Lp(a) and other lipoprotein lipid and apolipoprotein levels. It was concluded that hyperLp(a) aemia may be an independent risk factor in the development of premature atherosclerosis in patients with nephrotic syndrome.

訂正日: 2006/03/27 訂正理由: - 訂正箇所: PDFファイル訂正内容: -

抄録

Lipoprotein (Lp)(a) concentrations were measured in eight patients with nephrotic syndrome in the age range of 8 to 69 yrs. Mean (±SE) levels of serum Lp(a) were elevated in the nephrotic patients compared to controls (76.5±19.7 vs 18.6±0.9 mg/dl, p<0.001). After treatment with prednisolone, Lp(a) concentrations were decreased from 85.2±21.6 to 42.2±14.0 mg/dl. During the treatment, serum total cholesterol showed a negative correlation with serum albumin concentration. However, no correlation was noted between Lp(a) and serum albumin concentration. There were no significant correlations between Lp(a) and other lipoprotein lipid and apolipoprotein levels. It was concluded that hyperLp(a) aemia may be an independent risk factor in the development of premature atherosclerosis in patients with nephrotic syndrome.

責任著者(Corresponding author)

訂正情報

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