Primary Esophageal Non-Hodgkin's Lymphoma

Tetsuya TSUKADA; Toshiyuki OHNO; Hisakazu KIHIRA; Masanori TANIGUCHI; Takahiro TAKAHASHI; Shinobu ARIMA; Hiroyuki YAMADA; Yoshikazu AKASAKA; Hajime YOKOI; Kenkichi KITA; Tohru KOBAYASHI; Shigeru SHIRAKAWA

doi:10.2169/internalmedicine.31.569

Tetsuya TSUKADA, Toshiyuki OHNO, Hisakazu KIHIRA, Masanori TANIGUCHI, Takahiro TAKAHASHI, Shinobu ARIMA, Hiroyuki YAMADA, Yoshikazu AKASAKA, Hajime YOKOI, Kenkichi KITA, Tohru KOBAYASHI, Shigeru SHIRAKAWA

Author information

Tetsuya TSUKADA
the Second Department of Internal Medicine, Mie University School of Medicine
Toshiyuki OHNO
the Second Department of Internal Medicine, Mie University School of Medicine
Hisakazu KIHIRA
the Second Department of Internal Medicine, Mie University School of Medicine
Masanori TANIGUCHI
the Second Department of Internal Medicine, Mie University School of Medicine
Takahiro TAKAHASHI
the Second Department of Internal Medicine, Mie University School of Medicine
Shinobu ARIMA
the Department of Otorhinolaryngology, Mie University School of Medicine
Hiroyuki YAMADA
the Department of Otorhinolaryngology, Mie University School of Medicine
Yoshikazu AKASAKA
the First Department of Surgery, Mie University School of Medicine
Hajime YOKOI
the First Department of Surgery, Mie University School of Medicine
Kenkichi KITA
the Second Department of Internal Medicine, Mie University School of Medicine
Tohru KOBAYASHI
the Second Department of Internal Medicine, Mie University School of Medicine
Shigeru SHIRAKAWA
the Second Department of Internal Medicine, Mie University School of Medicine

Keywords: malignant lymphoma, gastrointestinal tract, T cell, chemotherapy, radiation

JOURNAL FREE ACCESS

1992 Volume 31 Issue 4 Pages 569-572

DOI https://doi.org/10.2169/internalmedicine.31.569

Details

Abstract

A 77-year-old woman with primary esophageal non-Hodgkin's lymphoma in clinical stage I_EA (Ann Arbor Classification) developed pain and difficulty in swallowing. An upper gastrointestinal examination revealed a submucosal tumor from the upper to the middle portion of the esophagus. Histopathological examination at endoscopic biopsy with endoscopic partial incision showed non-Hodgkin's lymphoma(diffuse type-large cell). Immunohistological examination of tumor cells disclosed LCA (+), CD3 (DAKO) (+), MT1 (+), UCHL1(+), MB1 (+), MxPanB (-) and EMA (-) reactivity and showed T cell lymphoma. The clinical stage was determined to be I_EA after further work-up. Improvement of swallowing difficulty and esophageal findings on upper gastrointestinal series were noted after modified CHOP therapy and radiotherapy (total 50Gy).
(Internal Medicine 31 : 569-572, 1992)

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