Protothecosis in a Patient with Systemic Lupus Erythematosus

Kazuyuki TSUJI; Junko HIROHARA; Yasushi FUKUI; Shigeru FUJNAMI; Yasuko SHIOZAKI; Kyoichi INOUE; Miyuki UOI; Hiroshi HOSOKAWA; Yasuo ASADA; Noritsuna TOYAZAKI

doi:10.2169/internalmedicine.32.540

Kazuyuki TSUJI, Junko HIROHARA, Yasushi FUKUI, Shigeru FUJNAMI, Yasuko SHIOZAKI, Kyoichi INOUE, Miyuki UOI, Hiroshi HOSOKAWA, Yasuo ASADA, Noritsuna TOYAZAKI

Author information

Kazuyuki TSUJI
the Third Department of Internal Medicine, Kansai Medical University
Junko HIROHARA
the Third Department of Internal Medicine, Kansai Medical University
Yasushi FUKUI
the Third Department of Internal Medicine, Kansai Medical University
Shigeru FUJNAMI
the Third Department of Internal Medicine, Kansai Medical University
Yasuko SHIOZAKI
the Third Department of Internal Medicine, Kansai Medical University
Kyoichi INOUE
the Third Department of Internal Medicine, Kansai Medical University
Miyuki UOI
the Department of Dermatology, Kansai Medical University
Hiroshi HOSOKAWA
the Department of Dermatology, Kansai Medical University
Yasuo ASADA
the Department of Dermatology, Kansai Medical University
Noritsuna TOYAZAKI
the Department of Public Health Research Institute of Kobe City

Keywords: immunocompromised host, opportunistic infection, achloric algae, prednisolone

JOURNAL FREE ACCESS

1993 Volume 32 Issue 7 Pages 540-542

DOI https://doi.org/10.2169/internalmedicine.32.540

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Abstract

A rare case of protothecosis in a 40-year-old Japanese woman with systemic lupus erythematosus, under long-term prednisolone treatment is presented. The patient developed extensive ulcerative skin lesions after injury. The characteristic histopathological findings and biochemical sugar assimilation tests indicated infection by Prototheca wicherhamii. The lesions improved following treatment with amphotericin B. The immunodeficient state of this patient seemed to contribute to the infection with Prototheca.
(Internal Medicine 32: 540-542, 1993)

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