Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Hepatitis in an Adult with Rubella
Yukihiko TAMEDAYoshitane KOSAKAKatsuya SHIRAKIYohei OHASHIMinoru HAMADAMitsukazu MIYAZAKINobuyasu ITOKoujiro TAKASETakeshi NAKANO
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1993 Volume 32 Issue 7 Pages 580-583


Rubella was accompanied by hepatic dysfunction in a 28-year-old male. Serum aminotransferase levels were moderately elevated and LDH markedly increased, especially LDH isoenzyme 5, whereas total bilirubin and ALP remained almost normal. GOT, GPT and LDH levels were completely normalized by the 21st hospital day. Paired antibody titers of viruses which may cause hepatitis, other than rubella, were of no significance. Laparoscopy showed grosse rote Leber. Histologic and electron microscopic findings of the liver were consistent with acute hepatitis. Hepatic damage with rubella is rare, and it is possible that the hepatic dysfunction seen in adult rubella may be mediated by an immunopathologic mechanism.
(Internal Medicine 32: 580-583, 1993)

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