Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Insulin Autoimmune Syndrome after the Third Therapy with Methimazole
Mutsumi HAKAMATAMitsuyasu ITOHYuichiro SUDONorikazu MIYATA
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JOURNAL FREE ACCESS

1995 Volume 34 Issue 5 Pages 410-412

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Abstract

In 1986, a 26-year-old female had been diagnosed as having Graves' disease and had been treated with methimazole for four months. After the treatment with propylthiouracil for another four months, she had been treated with methimazole once again. She was in complete remission for two years. She again experienced symptoms of hyperthyroidism, and treatment with methimazole was started again. On the thirteenth day after treatment, she experienced hypoglycemic attacks with skin eruption. The plasma glucose was 57 mg/dl, 125I-Insulin binding 69%, free IRI 196 μU/ml. The patient had the HLA-DRB1 *0406.
(Internal Medicine 34: 410-412, 1995)

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© The Japanese Society of Internal Medicine
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