Chronic Bronchobronchiolitis Obliterans Associated with Stevens-Johnson Syndrome

Jun YATSUNAMI; Yoichi NAKANISHI; Hiroaki MATSUKI; Kentaro WAKAMATSU; Koichi TAKAYAMA; Masayuki KAWASAKI; Hideo OGINO; Shuichi HASHIMOTO; Nobuyuki HARA

doi:10.2169/internalmedicine.34.772

Jun YATSUNAMI, Yoichi NAKANISHI, Hiroaki MATSUKI, Kentaro WAKAMATSU, Koichi TAKAYAMA, Masayuki KAWASAKI, Hideo OGINO, Shuichi HASHIMOTO, Nobuyuki HARA

Author information

Jun YATSUNAMI
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
Yoichi NAKANISHI
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
Hiroaki MATSUKI
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
Kentaro WAKAMATSU
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
Koichi TAKAYAMA
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
Masayuki KAWASAKI
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
Hideo OGINO
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
Shuichi HASHIMOTO
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
Nobuyuki HARA
the Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University

Keywords: obliterative bronchobronchiolitis, erythema multiforme, bronchography, bronchial occlusion

JOURNAL FREE ACCESS

1995 Volume 34 Issue 8 Pages 772-775

DOI https://doi.org/10.2169/internalmedicine.34.772

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Abstract

We report a case of bronchobronchiolitis obliterans associated with Stevens-Johnson syndrome diagnosed using bronchography and bronchoscopy in a 25-year-old man with dyspnea. Eighteen months prior to admission, the diagnosis of Stevens-Johnson syndrome due to anticonvulsant therapy was made at another hospital. On admission, the patient was wheezing and had overinflation of the lungs, with marked obstructive pulmonary dysfunction. Ventilation and perfusion scintigrams revealed multiple ventilation and perfusion defects but not mismatch. Bronchography revealed central bronchiectasis and obstruction of the peripheral bronchi. Occlusion of the fifth right basal bronchus was observed with fiberoptic bronchoscopy. Bronchography and bronchoscopy provide useful information for the diagnosis of this disease.
(Internal Medicine 34: 772-775, 1995)

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