Non-Insulin-Dependent Diabetes Mellitus Complicated with Idiopathic Hypoparathyroidism

Hiroyuki ITOH; Yuzo MATSUDA; Mitsuru NISHIYAMA; Takao KITAGAWA; Tomoko KOBAYASHI; Yutaka NIO; Satoshi HAMA; Hidemi HOSOGI; Tadashi HIROI; Kozo HASHIMOTO

doi:10.2169/internalmedicine.34.904

Hiroyuki ITOH, Yuzo MATSUDA, Mitsuru NISHIYAMA, Takao KITAGAWA, Tomoko KOBAYASHI, Yutaka NIO, Satoshi HAMA, Hidemi HOSOGI, Tadashi HIROI, Kozo HASHIMOTO

Author information

Hiroyuki ITOH
the Department of Internal Medicine, Hosogi Hospital
Yuzo MATSUDA
the Department of Internal Medicine, Hosogi Hospital
Mitsuru NISHIYAMA
the Department of Internal Medicine, Hosogi Hospital
Takao KITAGAWA
the Department of Internal Medicine, Hosogi Hospital
Tomoko KOBAYASHI
the Department of Internal Medicine, Hosogi Hospital
Yutaka NIO
the Department of Internal Medicine, Hosogi Hospital
Satoshi HAMA
the Department of Internal Medicine, Hosogi Hospital
Hidemi HOSOGI
the Department of Internal Medicine, Hosogi Hospital
Tadashi HIROI
the Department of Neurology, Hosogi Hospital
Kozo HASHIMOTO
the Second Department of Internal Medicine, Kochi Medical School

Keywords: hypocalcemia, insulin secretion, oculomotor nerve palsy

JOURNAL FREE ACCESS

1995 Volume 34 Issue 9 Pages 904-907

DOI https://doi.org/10.2169/internalmedicine.34.904

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Abstract

We report a case of non-insulin-dependent diabetes mellitus (NIDDM) complicated with idiopathic hypoparathyroidism. A 74-year-old male was hospitalized because of diplopia. He was revealed to have NIDDM. The levels of serum Ca and intact-PTH were 6.3 mg/dl and <5 pg/ml, respectively. Brain computed tomography revealed abnormal calcification in the cerebral basal ganglia and the cerebellum. After recovery from hypocalcemia, the endogenous insulin secretion was normalized. It is suggested that the pathogenesis of NIDDM in this patient may have been related to an insulin secretory defect as a result of hypocalcemia in addition to the hereditary risk.
(Internal Medicine 34: 904-907, 1995)

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