Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Disseminated Nontuberculous Mycobacteriosis Caused by Mycobacterium kansasii in a Patient with Myelodysplastic Syndrome
Takuya KOMENOTakayoshi ITOHKouji OHTANIMasaharu KAMOSHITAYuichi HASEGAWAMitsuo HORIToshitaka KOBAYASHIToshiro NAGASAWATsukasa ABE
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1996 Volume 35 Issue 4 Pages 323-326

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Abstract

A 38-year-old man with pancytopenia due to myelodysplastic syndrome exhibited persistent pyrexia and mediastinal lymphadenopathy. A biopsy specimen of the lymph nodes showed diffuse infiltration of epitheloid cells, including acid-fast bacilli identified as Mycobacterium kansasii. Cultures from gastric lavage and stool yielded M. kansasii, and granulomas were found in the bone marrow. A diagnosis of disseminated nontuberculous mycobacteriosis (DNTM) was established. The patient's condition improved after treatment with isoniazid, rifampicin, ethambutol and granulocyte colony-stimulating factor. Although DNTM due to M. kansasii is rare in Japan, it should be recognized as a possible cause of opportunistic infections.
(Internal Medicine 35: 323-326, 1996)

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