Rhabdomyolysis and Myocardial Damage Induced by Palytoxin, a Toxin of Blue Humphead Parrotfish

Hiroshi OKANO; Hiroshi MASUOKA; Shigeru KAMEI; Tetsuya SEKO; Sukenari KOYABU; Katsunobu TSUNEOKA; Takuya TAMAI; Kunihiko UEDA; Shigeo NAKAZAWA; Masahiro SUGAWA; Hideo SUZUKI; Masatoshi WATANABE; Ryuichi YATANI; Takeshi NAKANO

doi:10.2169/internalmedicine.37.330

Hiroshi OKANO, Hiroshi MASUOKA, Shigeru KAMEI, Tetsuya SEKO, Sukenari KOYABU, Katsunobu TSUNEOKA, Takuya TAMAI, Kunihiko UEDA, Shigeo NAKAZAWA, Masahiro SUGAWA, Hideo SUZUKI, Masatoshi WATANABE, Ryuichi YATANI, Takeshi NAKANO

Author information

Keywords: myosin light chain, creatine phosphokinase, food poisoning

JOURNAL FREE ACCESS

1998 Volume 37 Issue 3 Pages 330-333

DOI https://doi.org/10.2169/internalmedicine.37.330

Details

Abstract

A 55-year-old man had rhabdomyolysis and myocardial damage induced by palytoxin. Weakness and myalgia of four extremities occurred five hours after eating a fish. Rhabdomyolysis developed and the serum creatine phosphokinase (CK) was elevated to 40, 000 IU/ι on the 3rd day. Gastric lavage with activated charcoal and forced mannitol-alkaline diuresis therapy were performed. The patient recovered with no complication such as renal failure. In this case, palytoxin was suggested to induce myocardial damage which was demonstrated by an elevation of the myosin light chain level and a change in electrocardiogram.
(Internal Medicine 37: 330-333, 1998)

Corresponding author

Register with J-STAGE for free!