Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Intravenous Immunoglobulin Therapy for Diabetic Amyotrophy
Tomoko OGAWATomohiro TAGUCHIYasuhumi TANAKAKunihiko IKEGUCHIImaharu NAKANO
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2001 Volume 40 Issue 4 Pages 349-352

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Abstract

A 49-year-old woman with diabetes mellitus developed progressive weakness and atrophy of both thighs rendering her wheelchair-bound within two months. The neurological findings and electrophysiological test results were compatible with diabetic amyotrophy (DA). Immediately after intravenous immunoglobulin (IVIg) therapy (20 g×3 days), she became able to walk with a cane. After the next course of the therapy, she could walk without assistance. This dramatic effect of IVIg therapy together with the recent observation of vasculitic neuropathy in DA indicates an inflammatory process in this condition, and gives support to this treatment for DA.
(Internal Medicine 40: 349-352, 2001)

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