Antineutrophil Cytoplasmic Antibody (ANCA)-associated Glomerulonephritis with Intrarenal Aneurysms and Renal Arteriovenous Fistulaes

Akihito INATSU; Jun SHIMIZU; Satosi OOSHIMA; Susumu MATSUKUMA; Kozaburo KOGA; Shigeyo SHIWACHI; Teizo ITO; Hiroko YASUDA; Takao KUBOTA

doi:10.2169/internalmedicine.41.853

Akihito INATSU, Jun SHIMIZU, Satosi OOSHIMA, Susumu MATSUKUMA, Kozaburo KOGA, Shigeyo SHIWACHI, Teizo ITO, Hiroko YASUDA, Takao KUBOTA

Author information

Akihito INATSU
Department of Internal Medicine, Japan Self Defense Forces Central Hospital
Jun SHIMIZU
Department of Internal Medicine, Japan Self Defense Forces Central Hospital
Satosi OOSHIMA
Department of Internal Medicine, Japan Self Defense Forces Central Hospital
Susumu MATSUKUMA
Department of Pathology, Japan Self Defense Forces Central Hospital
Kozaburo KOGA
Department of Internal Medicine, Japan Self Defense Forces Central Hospital
Shigeyo SHIWACHI
Department of Internal Medicine, Japan Self Defense Forces Central Hospital
Teizo ITO
Department of Internal Medicine, Japan Self Defense Forces Central Hospital
Hiroko YASUDA
Department of Internal Medicine, Japan Self Defense Forces Central Hospital
Takao KUBOTA
Department of Internal Medicine, Japan Self Defense Forces Central Hospital

Keywords: ANCA, aneurysms, arteriovenous fistulaes

JOURNAL FREE ACCESS

2002 Volume 41 Issue 10 Pages 853-858

DOI https://doi.org/10.2169/internalmedicine.41.853

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Abstract

A 78-year-old Japanese man was admitted with a complaint of slight fever and weight loss. At admission, he tested positive for myeloperoxidase (MPO)-ANCA and had renal failure. An abdominal angiography revealed atrophy of the right kidney, two or more arteriovenous fistulae (AVF) in the right renal interlobular arteries, and multiple ancurysms in both kidneys. A renal biopsy specimen showed diffuse crescentic glomerulonephritis accompanied by tubulo-interstitial changes. This case suggests the possibility of some relationship between ANCA-associated vasculitides and the formation of aneurysms and AVFs.
(Internal Medicine 41: 853-858, 2002)

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