Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
Exogenous Lipoid Pneumonia Following Ingestion of Liquid Paraffin
Akihiko OHWADAYasuko YOSHIOKAYuri SHIMANUKIKeiko MITANIToshio KUMASAKATakashi DAMBARAYoshinosuke FUKUCHI
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Volume 41 (2002) Issue 6 Pages 483-486

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Abstract

An asymptomatic patient with exogenous lipoid pneumonia (ELP) due to silent aspiration of liquid paraffin ingested as a lubricant was diagnosed by bronchoalveolar lavage (BAL). BAL fluid separated into oily upper phase and lower aqueous phase spontaneously. Microscopic analysis of BAL cells revealed the presence of lipid-laden alveolar macrophages. Classic histochemical staining and electron microscope examination indicated that neutral lipid was dominant but phospholipid was also present in the lipid-laden macrophages. Together with the history of ingestion of liquid paraffin, we identified that the ingested liquid paraffin was the origin of the neutral lipid in the lipid-laden macrophages observed in the BAL fluid.
(Internal Medicine 41: 483-486, 2002)

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