Abstract
The etiology of fatigue is unknown, and as tuberculosis has many factors, the rise and fall of resulting substances of fatigue are very complicated. The author conducted a study on the concentration of lactic acid relating with fatigue and the influence of bed-rest upon it. Healthy persons selected with conditions of occupation, age, sex, time and TB patients were under measurements.
1) Average of lactic acid in sera of healthy persons was x=26.0±2.72mg%. Differences by sex can be found.(Fo=5.9>5.75)
2) The figure in the slight cases of TB was almost equal to that of healthy persons.
3) The figure in the serious was 50 to 80mg%. This may be explained from the shortage of oxygen due to the disturbance of respiratory areas.
4) By surgical operation of lungs, the figure increased to 50 to 100mg%. Incidentally, one case showed gradual decrease and other case showed increase later. These fluctuation may be resulted from the supply of oxygen, Vitamin B, , or the process in liver.
5) Practically, no differences of concentration in urine were found. The quantities of lactic acid in urine were almost equal at any degree (I to degrees) of bed-rest, howeber, remarkable increases were found at IV degree of bed-rest.
6) At most, II degree of bed-rest should be kept for 6 month of hospitalization.
