Abstract
Chemotherapy was given to 26 cases who had been discharging infrequently bacilli of 1 to 10 colonies after surgical treatments of pulmonary tuberculosis, and whose opposite lung were not the source. Effects of the chemotherapy were investigated with regard to the degrees of negative conversion. Incidentally, all patients were of stable condition and without significant findings by radiological and bronchoscopic examination.
Twenty-one cases were treated with SM + PAS, 1 case, with INH + PAS and 4 cases, with Tibion alone.
The results were as follows:
By 2 months' treatment, negative conversion was 76.9%; by 6 months, 66.6% and by 11 months, 27.8%, that indicate remarkable decrease in the rate of negative conversion with the duration of time.
To expect complete negative conversion in these cases was impossible. However, we must admit this therapy as an effective medical treatment of the cases.
By dividing these patients to bed-rest group and prominade group during chemotherapy, another observation was attempted to see the relation between negative conversion and rest grade after treatment. The prominade group was better than the bed-rest group in their negative conversion rate.