抄録
Tests on the liver functions of 26 patients hospitalized at Setagaya National Hospital were carried out before, during, and after surgical operations under general anaesthesia.
Results are as follow:
1) Liver functions such as Takada reaction, C. C. F., total serum bilirubin, B. S. P., serum alkaline phosphatase, and A/G ratio became worse by the administrations of ether and Cyclopropane for a while and recovered slowly with time. There were difference in the grade of tests results between the patients with diseased liver and the patients with normal liver. Whereas in the latter cases liver function recovered almost to normal level after 3-5 days, patients with slightly or moderately disturbed livers recovered after 7-14 days. Patients with seriously damaged liver were very slow in recovery and in some cases no sign of recovery could be observed after 2 weeks.
2) The complications of inhalation anaesthesia occur often in the patients with liver disease so that some of the patients with such affection have to avoid not only operation but also the general anaesthesia. In some cases, hypothermia might de necessary.
3) General anaesthesia should be carefully administered for those patients who have liver disease. Good nutrition and ample supply of oxygen are also necessary for the protection of liver from damage.
4) B. S. P., serum alkaline phosphatase and A/G indicate the status of liver function rather well and therefore can be utilized for testing liver function. However, the liver function as a whole can only be judged by the comprehensive review of repeated tests and by use of clinical judgement.
