Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
On the Chemical Treatments and the Nutritive Method for the TB-Infected Mice
(2)
Seiji SUZUKI
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1959 Volume 13 Issue 9 Pages 694-701

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Abstract
In the first report the author described the body weight and the nutritive methods with the non-TB infected mice. The similar nutritive methods were applied at this study and the applied factors were the same; DD strain mice, Aoyama bacillus, streptomycin and INH.
Results are as follow:
1) TB infected mice were fed by 5 methods. Death rate was remarkably high among a group of mice nourished by low protein. The fat was needed, however, the protein was found to be more important to live.
2) When infected mice are treated by INH, increase of body weight is noticed among the mice which are fed with high protein. On the contrary, decrease of the body weight is seen among the mice which are feed with low protein and high fat diet.
3) During the period of chemotherapy, the relation between the nutritive method and the total bacillus quantity in the lung, liver and spleen of the mouse was examined. However, no remarkable difference was noticed. Growing colony in lung was less in case of SM treatment than of INH treatment.
4) When TB bacillus was inoculated in the tail vein, tubercle grew mostly in the lung. But the appearance of this tubercle showed no difference between the mice with high and low protein diet.
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