Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
On the Effects of the Brgnchial Instillation of Antituberculaus Remedies into the Cavities in Pulxnandry Tuberculosis
Yosimi HARADAHaaime GOTO
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1961 Volume 15 Issue 2 Pages 110-123

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Abstract
To treat the tuberculous cavities of the lung the author used the instillation method with the aqueous solution of Streptomycin, Hydrazid, INHG, etc, via bronchus into cavities, This is a similar remedial principle, which in surgical treatment an injury is finally cured on the basis of scars caused by locally applied medicines.
In the therapy with the above mentioned method we expected not only the condensation or diminishing of cavities but also finally their disappearance.
1. The experiments were performed on 30 cases of cavernous tuberculous patients who were with slight or far-advanced forms.
2. Using Metras cannula the aqueous solution combination of SM and INH or INHG alone were given into cavities. For the early period of the treatment these drugs were administered weekly and then later once every other week.
Results
The instillation method revealed a remarkable improvement on the cavities as well as in the general clical features.
1. 24 cases out of 30 cases (76.6%) had favorable results, particularly 14 cases out of the 24 cases showed magnificent improvement; cavities disappearance roentgenologically as well as markedly improved clinical findings.
2. It is concluded that bronchial instillation with antituberculous drugs have proven improved to be a very effective method for treating tuberculous cavities, since there were no noticeable side-effect or undesirable phenomena during the period of the treatment.
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