Abstract
Three methods of preventive inoculation including polyvalent influenza adjuvant vaccine were applied to 150 patients with pulmonary tuberculosis in our sanatorium and the following results were obtained.
1) Side effects of 0.1ml adjuvant vaccine of flu A1, A2 and B 500 CCA/ml were mild intramuscularly. Eight cases showed accelerated sedimentation rates a week after the injection, and 6 out of 8 cases showed formol sedimentation rates 2 weeks after the injection.
2) Both 0.1ml intradermal injection and two times of 0.5ml subcutaneous injections of fluid vaccine of flu A1, A1 and B 300 CCA/ml also showed mild side reactions.
3) Hemagglutination-inhibition antibody (HI) titers of flu A2 showed a remarkable elevation in each 3 methods of the inoculation, and no remarkable difference about the elevation of HI titers between of patients with pulmonary tuberculosis and of healthy persons was observed.
4) No remarkable difference on the elevation of HI titers among types of pulmonary tuberculosis was recognized.
Therefore, the preventive inoculation of influenza vaccine in patients with pulmonary tuberculosis should be enforced.
