抄録
The author described techniques and effects of therapeutic hypothermia in neurosurgical practice at The 1st Tokyo National Hospital.
The techniques used are artificial hibernation and mild hypothermia. For the former “lytic cocktial M1” after Laborit (Wintermin 1, Pyrethia 1, Opistan 2), for the latter placing the patient in contact with several bags containing ice at head, neck, axillary groove and inguinal region are used. The degree of hypothermia obtained varies from a restoration of normal temperature to a lowering general body temperature to 35.5°C to 36°C of rectal one.
Fifteen cases of severe head injury, 10 cases of immediate postoperative dysfunction of brain tumor and each one cases of apoplexy, encephalitis and brain damage due to anoxia during general anesthesia, were treated with this procedure.
All severe head injury cases had neuro-vegetative signs due to compressing brain stem (unconsciousness, hyperthermia etc.). They recovered from the cerebral trauma with our hypothermia except one boy of six years old who had hemorrhagic diathesis.
Immediate postoperative unconsciousness and hyperthermia of brain tumor patients were treated by our hypothermia with sucess. This patientY had been critically ill previously.
A patient with apoplexy who recovered well without hyperthermia by our hypothermia.
A patient with encephalitis was treated with our procedure for 60 days keeping her rectal temperature around 36.5°C. Her hyperthermia disappeared with improving her consciousness, and she recovered without sequellae.
A patient with brain damage after anesthesia passed through dangerous period with our hypothermia.
