抄録
There is increasing recognition of the infections due to gram-negative bacilli which were antibiotic resistant. Present study revealed a annual changing pattern of sensitivities of gram-negative bacilli which were isolated from materials of clinical sources. Antibiotic sensitivities of 2885 strains (except Salmonella) gained during a period from April of 1958 to March of 1935 at the First National Hospital were investigated by the technique with disks for streptomycin, chloramphenicol, tetracycline, kanamycin, colimycin and sulfapreparation.
Results:
1) It is noted that increasing numbers of resistant strains of gram-negative bacilli during a period from 1958 to 1960 was evident, although a slight decreasing tendency was seen after 1961 as a whole. More details, however, must be necessary on the changes of sensitivity for each antibiotic.
2) On 346 strains which were sensitive to one of six tested antibiotics, 76.2% were sensitive to colimycin and 17.9% to kanamycin. On 113 strains out of these which belong to Family Enterobacteriaceae, 52.2% were sensitive to kanamycin, 42.5% to colimycin and 3.5% to streptomycin.
3) On 521 strains which were sensitive to two of six tested antibiotics, 68.7% were sensitive to kanamycin and 84.1% to colimycin. On 293 strains out of these which belong to Family Enterobacteriaceae, 93.6% were sensitive to kanamycin and 75.1% to colimycin.
