Abstract
As Betke's stain for detecting changes of HbF in both erythroblasts and erythrocytes, we have adopted the direct method in our investigation on the fetal cell level of new born infants and infants including congenital anomalies. Sixty-two cases of new born infants and infants, 20 cases of patients with blood diseases have been examined. The results of our experiments revealed following changes:
1) Most of congenital anomalies showed the tendency of rapidly decreasing in their fetal cell level, though the level at the birth was their normal limit.
2) The case, revealed representation of fetal cells, were only founded among the patients suffering from congenital-, acquired aplastic anemia and leukemia, treating with corticosteroid.
3) The infants, had more than 10% of fetal cell level 6 months later from birth, were mostly premature infants with low weight.