Abstract
This report deals with the count of circulating eosinophils and basophils in 86 patients with various kind of goiter during a year and one month from July 1965 to July 1966, This work has been made as a part of the study to evaluate the biological meaning of the number of circulating eosinophils and basophils in various experimental animals and human beings during past ten years.
In the first place, blood was taken from the ante-cubital vein of the patients during the time about 10 a, m. to noon and the number of eosinophils and basophils was counted using Manner's staining method and Arase's staining method.
In addition, to make sure the diagnosis, B. M, R, 131I-24-hour Thyroidal uptake, 131I-Resin Sponge uptake etc. were examined and Scintigram was performed.
Among 86 cases, 17 patients with untreated Graves' disease and Plummers' disease showed eosinophils below 50/mm3 and basophils below 10/mm3.
About 22 patients who had been treated already, both of Graves' disease and Plummers' disease, showed inrceased number of eosinophils and basophils. The same result was obtained in the patients with nontoxic goiter.
Moreover, sequential observation of circulating eosinophils and basophils during the proper treatment on the hyperthyreosis revealed that the gradual increase of eosinophils occured at first and followed by the increase of basophils.
From the results of this experiment, the count of circulating eosinophils and basophils seems to be highly valuable for the differential diagnosis of thyroid disease and to decide the treatment of Hyperthyreosis.
