Abstract
The activities of enzymes, cholinesterase (ChE), creatine phosphokinase (CPK), glutamic oxalactic transaminase (GOT), lactic dehydrogenase (LDH) and inhibiting activity of ChE by dibucaine (DN) in serum were measured in 40 patients of progressive muscular dystrophy (PMD).
Forty cases of PMD were classified in 34 cases of Duchenne type, 5 cases of limb-girdle type and 1 case of facioscapulohumeral type.
Results:
1) The activities of ChE in each PMD were measured for 3 times during 3 months and they were equal to normal human subjects.
2) There were no significant relationship between the activities of ChE in each PMD and the activities of the other enzymes; CPK, GOT and LDH.
3) The activities of DN in each PMD were fixed regardless of the activities of the other enzymes; ChE, CPK, GOT and LDH.
