Abstract
A study on the activities of creatin-phosphokinase (CPK), lactic dehydrogenase (LDH) and aldolase in sera was carried out for 137 cases of progressive muscular dystrophy (PMD) and their relatives.
In patients of Duchenne type of PMD, it was reconfirmed that an elevation of serum CPK activity was much more remarkable than that of the other enzyme activities.
The frequency of abnormalities in the CPK activity was about 20 per cent in mothers of Duchenne type of this disease, while that in aldolase and LDH was only a few per cent.
A correlation in the increases of CPK and the other enzymes was not found in relatives of the patients.
