抄録
Experimental pyelitis and pyelonephritis on the mechanism of retrograde urinary infections were previously reported.
At this experiment staphylococci or E. coli were infected on rabbits intravenously. The experimental method was generally the same as that of retrograde urinary infections.
The staphylococci injected intravenously were found at every part of renal substance, but not equally and much at pelvic substance. Pathological renal change was pyelonephritis, but in the contrast rabbits which were not sensitized there were only transient changes and no pyelonephritis. On hematogenous infections pyelonephritis was occurred from the beginning and pyelitis was not. In this case the antigen-antibody reacticn was necessary in hosts. In the cases that E. coli were injected intravenously the renal changes were little and pyelonephritis were not found. By the experiments it was thought that the mechanism of hematogenous infections on pyelonephritis related to the sort of bacilli.
From the mechanism of urogenous and hematogenous infections, in the retrograde urinary infections there were the case of pyelonephritis fprogressed fvom pyelitis, cr pyelonephritis from the outset, but on the hematogenous infections pyelonephritis would be from the beginning. And it was thought in these cases some sorts of conditions on hosts were necessary and the one of conditions was the antigen-antibody reaction, though the antigens were different.
Clinically, too, there were pyelitis and pyelonephritis, but it was thought that it was very difficult to diagnose the case as pyelitis or pyelonephritis.
