Abstract
We reported two cases of so-called “Clover-leaf Skull Syndrome” which recently appeared in articles of German, American, British and Japanese Medical Journals.
The second case was seen in twin babies and seemed to be the first case appeared in twins.
The cause of this syndrome was discussed from hereditary, medicinal and radiational view points. The chromosomal analysis showed quite normal pattern in both cases.
We thought the syndrome is a congenital skeletal disorder showing high degree of skull deformity consisting with craniosynostosis of the basal bones, honeycomb-like skull deformity, partial membranous alteration of the skull, chiefly in parietal bone and abnormal opening of the saggital suture.
The bony deformity is often extended to the long bones and it is various form and considerably symmetrical.