Abstract
A 14-years-old female patient complained of general fatigue and headache and then nausea and vomiting since June 1966. Spinal fluid examination disclosed initial pressure of 300mmH2O, 3/3 cell count and 10mg% total protein. On 2nd August, 1966 she was hospitalized with high fever and severe vomiting. On physical examination at admission revealed Babinski's sign and Kernig's sign were elicited but eruption, motor and sensory deficit were not found. In April 1968 SLE was diagnosed because of appearance of butterfly shaped flush eruption on the cheeks and purpura on the extremities and oral cavity. Severe thrombocytopenia was found and in the bone marrow disappearance of meta-megakaryocytes was observed, accordingly thrombocytopenic purpura combined with SLE was suspected. In October 1970, she complained of blurred vision caused by retinal edema. In May 1971, genital bleeding, cheek eruption, joint pain, thrombopenia, positive LE test, 128-1024× antinuclear factor, hypertension of the cerebrospinal fluid and visual disturbance etc. were observed. At present hypertension of the cerebrospinal fluid with optic atrophy have been persisted. Long-standing hypertension of the cerebrospinal fluid without pleocytosis and chemical changes is rare in SLE bibliographically.
