Abstract
Between 1966 and 1977, 50 patients were treated for superficial tumors of the urinary bladder at Atami National Hospital.
This is a statistical report on the recurrence of superficial bladder tumors and on the prophylactic effect of intravesical instillation of Mitomycin C on the tumor recurrence.
1) The recurrence of superficial bladder tumors was found in 21 of 50 patients (42.0%) and occured in most frequently within three years after first treatment, about three-fourth of all patients.
2) The recurrence rate of tumors in multiple type was slightly lower than in single tumors. The rate showed no significant difference between both groups.
3) The recurrence rate in the tumors of low grade was somehow higher than those of high grade. No significant difference of the recurrence rate was statistically found between the tumors of low grade and those of high grade.
4) The recurrence of tumors was frequently found in endoscopic operation (TUR TUC) than in partial cystectomy.
5) Intravesical instillation of MMC were employed for the purpose of prophylaxis of the recurrence of bladder tumors after removal of the tumor. Meaningful reduction of the recurrence was recognized in the postoperatively instillated group, compared with postoperatively non-instillated group. Recurrence rate of former was 9.2% after months follow up, while that of latter was 22.0%.
It is convinced that intravesical instillation of MMC may be effective for the prophylaxis of the recurrence after removal of tumor.
