Abstract
Recently, because of abusive administration of broad spectrum antibiotics, the concept of urinary tract infection has been changed seriously. Certainly Pseudomonas infection in the urinary tract is still a clinical problem of large magnitude but infections due to so-called non-pathogenic organisms, namely, Serratia marcescens, Pseudomonas cepacia are getting to play a large part nowadays.
We experienced 27 in-patient cases and 3 out-patient cases of Serratia marcescens infections in the urinary tract during August 1 to December 31, 1977 and a clinical analytical study was performed to make sure what was the most important objective to be solved.
The summary is written below. 1) Serratia marcescens has a predisposition for elderly and/or debilitated and for patients previously treated with broad spectrum antibiotics, 2) from the chemotherapeutic point of view, the most important problem is how to improve the poor physical condition due to multitudinous disorders, 3) the antibiotics to be administered have to be chosen with care, thus, sensitivity tests in vitro are not absolute stand-points. So, 4) the thetherapeutic and/or prophylactic measures should be considered in host-parasites-drugs relationship.
