Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
HLA TYPING TO DUCHENNE MUSCULAR DYSTROPHY (DMDs) AND THEIR PARENTS
Kyoko SAKAIKanichi NAKAGAWARAMitsuru YAMADA
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Keywords: HLA typing
JOURNAL FREE ACCESS

1985 Volume 39 Issue 2 Pages 175-179

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Abstract
HLA typing was performed in 93 patients with DMDs and their parents and other pa-tients with PMDs using a standard microlymphocytotoxicity test.
We confirmed the strong correlation with specific HLA antigens and its order in fre-quency in patients with DMD and their parents.
A slight increase in A10, AW33 and a slight decrease in A28, BW40, BW63 were char-acteristic as compared to male nephrotic controls.
BW6 was the most frequent locus including control groups but exceptionally BW4 was significantly frequent in SPMA.
The genetic significance of these HLA typing pattern was also discussed.
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© Japanese Society of National Medical Services
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