Abstract
The author experienced a typical case of policythemia vera accompanied by various complications, and reported the case with some previous literatures and clinical considera-tions.
In this case the numbers of erythrocyte, granulocyte and platelet were remarkably increased, and the bone marrow puncture revealed an increase in the numbers of three haematopoietic cellular classes and argentaffin fibers, dilatation of sinuses and innumerable formations of erythroblastic island, and Philadelphia chromosome and trisomy of C group were not present through chromosomal analysis. Clinically, this case developed cerebral infarction, myocardial infarction, atrial fibrillation, left homonymous hemianopsia, impaired hearing, renal dysfunction and hypertension which were primarily ascribed to hyperviscosity syndrome of polycythemia vera.
Furthermore, this case was accompanied by hypoglycemia and positive RA test, and the former was conceivably due to an increase in blood cells but the latter supported the ECG findings of myocardial infarction. The fact that the serum level of erythropoietin did not decrease in this case was likewise explained by renal hypoxia due to hyperviscosity syndrome seen in polycythemia vera.
