Abstract
We pointed out the problems of the antithrombotic drugs, and evaluated antithrombotic therapy after cardiovascular surgery in the Iwakuni National Hospital. The total number of the patients on antithrombotic therapy was 165 cases. The numbers of the patients with aorto-coronary bypass, valve replacement and arterial bypass by the vascular graft were 45, 50 and 70 cases, respectively. The mean age of the patients (124 males and 41 females) was 60.5±9.8 years, and the mean follow-up period was 40±16 months.
Major hemorrhagic complications were recognized in six patients, and three patients died of intracranial hemorrhage. Three patients were complicated with systemic thromboembolism, and were treated successfully by intensive care. In this study, the number of the patients with surgical management was 12 cases.
We conclude that the patients with mechanical valve replacement, arterial bypass by the vascular graft less than 6mm in diameter and a history of thromboembolism should be on both anticoagulants and antiplatelet agents.
