Abstract
One hundred and eighteen patients with end-stage renal disease under 18 years old in twenty-seven national sanatoriums up to August 1987 were studied through questionnaires. Their original diseases consisted of primary (61 cases) or secondery (11 cases) glomerular diseases, congenital renal and/or urinary tract anomalies (19 cases), Alport's syndrome (10 cases), chronic pyelonephritis (8 cases) and others (7 cases).
The onset and/or detection of the original disease was most frequent at the age from 6 to 9 years old (37 cases) and about 30 percent of patients were detected by mass-screening. Replacement therapy was started with hemodialysis in 71 patients, intermittent peritoneal dialysis in 28 and CAPD in 15, the latter having been increasing rapidly in recent years. Thirty-six patients had been introduced to renal transplantation (32 living, 3 cadaveric). At the last check up, 22 patients were alive with transplanted kidney, 61 were on dialysis, 17 were died and 16 were unknown. The survival rate at 1, 3 and 5 years was 91.6%, 81.6% and 78.8%, respectively. The major complications consisted of anemia (78.8%), hypertension (28.7%) and osteodystrophy (25.5%). The most common cause of death was cerebral hemorrhage (7 cases) and the prognosis of patients with lupus nephritis was poor. We pointed out some problems about early detection, diagnosis and treatment.
