Abstract
The concentration of serum digoxin was measured in 130 inpatients to see the correlation among dosage, age and the serum digoxin concentration.
The following results were obtained; The correlative equation was Y=0.47+0.74D/(140-A) (Y: serum digoxin concentration, ng/ml; D: dose/weight, mcg/kg; A: age, yr.), and the coefficient of correlation was 0.59. By putting Y=1.0 on the equation, the maintenance dose of digoxin can be calculated from weight and age, that is; the dose=0.71 (weight) (140-age).
