Abstract
A 52-year-old alcoholic man with liver cirrhosis was admitted because of jaundice, ascites, increases in serum transaminases, leucocytosis and fever. Leucocytosis and fever continued in spite of administration of antibiotics. From 35th hospital day, projection of his left eye and paralysis of his left III-IV cranial nerves appeared. He gradually became unconscious and died at 39th of hospital day. Autopsy findings revealed cerebral hemorrhage due to basal meningoencephalitis by mucormycosis infiltrated to the pia mater. In a patient with alcoholism and advanced liver cirrhosis, it is often difficult to discriminate neuropsychic symptoms of meningoencephalitis from alcoholic psychoses and hepatic encephalopathy. However, this case indicates that immediate and active antimycotic therapy is recommended, if characteristic findings of rhinocerebral rnucormycosis such as orbital symptoms with prolonged fever resistant to antibiotics are observed in a compromised host like a patient with alcohoic liver cirrhosis.
