Abstract
As for usual early symptoms of the primary vaginal cancer, there are irregular bleeding, abnormal flow, and demarked vaginal tumor. Recently, we experienced a patient with the primary vaginal cancer who complained chiefly anal pain. Pelvic examination revealed a large tumor with ulcerative lesion on the posterior vaginal wall and invasived widely. On admision, she was treated with systematic combination chemotherapy : BPM therapy (Bleomycin 5mg/body for day 1-5. Mitomycin C 6mg/body and Carboplatin 50mg/body on the day 5 in 1 course), for 5 courses and with local administration (Carboplatin 50mg/body once a week) for 16 times. With these chemotherapy the patient turned well with improvement of the anal pain and local visual findings in vagina and it decreased of the tumor marker (serum SCC) These changes were interpreted as effective chemotherapy.