A case of chronic idiopathic thrombocytopenic purpura (ITP) with an increased platelet count during the course of pulmonay abscess is reported. A 69-year-old woman with ITP was admitted to our hospital because of severe thrombocytopenia and hyperglycemia. The ITP had been diagnosed 2 years previously, splenectomy had been performed, and the platelet count was maintained at around 20, 000-30, 000/mm
3 with prednisolone, 10mg/day. Because the platelet count was 6, 000/mm
3 on a regular visit, the prednisolone dose was increased to 30mg/day. Two weeks later, the platelet count and fasting blood glucose were 2, 000/mm
3 and 212mg/dl, respectively, and she complained of polyuria and thirst. She was then admitted for further evaluation and treatment. After admission, platelet concentrate was infused, the prednisolone dose was reduced and cyclophosphamide was added. On the 18th hospital day, a fever up to 38°C developed with a platelet count of 10, 000/mm
3. A cavity and air-fluid level were noted in a chest X-ray and CT scan, and leukocytosis and increased serum C-reactive protein (CRP) were also found. Based on these findings a diagnosis of pulmonary abscess was made. Candida albicans and Klebsiella pneumoniae were cultured from the sputum, and cef azoline sodium and f luconazole were administered intravenously. The fever subsided in a week, and the CRP levels and leukocytosis became normal in 2 weeks. The platelet count increased to38, 000/mm
3 by one week, to 86, 000/mm
3 by 4 weeks after treatment of the pulmonary abscess, and remained at 50, 000-90, 000/mm
3 one year after admission on prednisolone 5mg/day. Cases of ITP exhibiting remission or increases in platelet count during infection are rare, only 12 cases have been reported in Japan to date.
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